Nasopharyngeal cancer is one of the malignant tumor of the head and neck which shows rather poor prognosis because of the late discovery of the disease, anatomical complexity for examination, difficulties in surgical treatment and high recurrence rate. Frequently, the initial symptom such as serous otitis media makes the doctor ignore underlying cause in the nasopharynx and misleads to inadequate treatment. So, to know the characteristic clinical findings of nasopharyngeal cancer is very important for the early detection of this malignant tumor. For this purpose, 158 cases of nasopharyngeal cancer which were treated at Seoul National University Hospital for the past 10 years were analyzed retrospectively. Following result were obtained: 1) One hundred and fourteen patients were male and forty four patients were female(M : F=2.6 : 1). Average age at diagnosis was 46 years old. 2) Cervical mass was the most common initial symptom and sign(72.1%) instead of presenting symptoms of primary tumor. 3) The mean duration from onset of initial symptom to diagnosis was 6 months. 4) Cranial nerve involvement was present in 45 patients(28%). The sixth cranial nerve was most frequently impaired. Next was the third cranial nerve. 5) Histopathologically, squamous cell carcinoma was 85 cases and mostly poorly differentiated. Undifferentiated carcinoma was 60 cases among 158 cases. 6) According to TNM system of AJCC, there were 121 cases(76.6%) of stage IV, 30 cases(19%) of stage III and 7 cases(4.4%) of stage II. 7) Most of cases were treated by radiation. Overall survival rate was 49%.