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Korean Journal of Otorhinolaryngology-Head and Neck Surgery 1963;6(1): 59-62. |
Severe Toxic Reaction Following Topical Application of Tetracaine |
Kwan Taek Noh, MD, Suk Hi Yi, MD, and Se Ung Chon, MD |
Department of Otolaryngology, Anesthesiology, ROK Naval Hospital, Chinhae, Korea |
Tetracaine 塗布麻醉後 甚한 Toxic Reaction을 일으킨 2症例 |
盧寬澤 · 李石熙 · 全世雄 |
鎭海 海軍病院 耳鼻咽喉科, 痲醉科 |
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ABSTRACT |
Severe toxic reactions and fatalities following the use of tetracaine have repeatedly been reported in the literature, and analysis of these reactions reveal, that practically all of these reactions have occurred after topical application. Recently we observed two cases of severe toxic reaction following topical application of 2% tetracaine solution in oral and pharyngeal mucosa. In both cases reactions were manifested with severe tonic convulsion and shock immediately after the use of tetracaine, and those cases were treated with oxygen inhalation and barbiturate injection. We also discussed the etiology, prevention and management of those reactions. |
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