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Korean Journal of Otorhinolaryngology-Head and Neck Surgery > Volume 19(4); 1976 > Article
Korean Journal of Otorhinolaryngology-Head and Neck Surgery 1976;19(4): 101-10.
Clinical Studies on the Salivary Gland Tumors
Seong Soo Kim, MD, and Jin Young Kim, MD
Department of Otolaryngology, College of Medicine, Seoul National University, Seoul, Korea
唾液腺腫瘍에 對한 臨床的 考察
金性洙 · 金鎭永
서울大學校 醫科大學 耳鼻咽喉科學敎室
ABSTRACT

Tumors of salivary glands are relatively rare but it is often taken for clinical malignancy due to its not uncommon metastasis and recurrence in spite of histopathological benignity. There is many debate on the histopathological classification and the developmental mechanism. We have the following result with the studies of 149 patients from 1960 to 1975 for 16 years. 1) Sex ratio of male to female is 1.3 : 1 and each average age is 46.8 yr and 43.3 yr. 2) Benign tumor is 1.4 times more frequent than malignant tumor and average age is 42.5 yr (benign) and 49.2 yr (malignant), so 6.7 yr is higher in malignant tumor. 3) The tumor incidence is 1.3 times more frequent in major salivary glands than minor. The parotid gland is the most frequent site with malignant tumor (13.0%) and benign tumor (52.9%) in major salivary glands. The palate is the most frequent site with malignant tumor (31.6%) and benign tumor (30.3%) in minor salivary glands. Malignancy is relatively more predominant in minor than in major salivary glands. 4) The most frequent histologic type is pleomorphic adenoma (56.4% of total tumor) and most of pleomorphic adenoma occurred in the parotid gland (41.0%) and the following frequency with the palate (21.0%), the submandibular gland (15.7%) etc. All three monomorphic adenoma is involved in the parotid gland. 5) In malignant tumor the site is various and same ratio in major and minor salivary glands with the following histologic frequency ; undifferentiated ca. (30.6%) epidermoid ca. (16.1%), adeno ca. (14.5%), mucoepidermoid ca. (14.5%), adenoid cystic ca. (12.9%), ca. in plemorphic adenoma (8.1%) and acinic cell ca. (4.8%). 6) It seems that myoepithelial and ductal epithelial cell has important roll in variety of tumor, any needle or limited biopsy is contraindicated to reduce metastasis and recurrence, initial adequate resection is the choice of treatment with forozen section during operation. 

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