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Korean Journal of Otorhinolaryngology-Head and Neck Surgery 1986;29(6): 912-22. |
Wegener's Granulomatosis |
Hae Sung Maeng, MD, Il Shik Shin, MD, Min Sik Kim, MD, Kwon Hee Won, MD, and Seung Ho Cho, MD |
Department of Otolaryngology, Catholic Medical College, Seoul, Korea |
Wegener씨 육아종증 |
맹해성 · 신일식 · 김민식 · 원권희 · 조승호 |
가톨릭대학교 의과대학 이비인후과학교실 |
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ABSTRACT |
Wegener's granulomatosis is an rare disease of unknown etiology but generally considered a hypersensitivity disorder. This disease was first described by Klinger in 1931 and noted as a distinct clinicopathological syndrome by Wegener in 1936, as rhinogenic granulomatosis ; necrotizing granuloma of upper or lower respiratory tract, generalized focal necrotizing angitis and a focal necrotizing glomerulitis. This disease is classified based on anatomic site of involvement ; classic form of Wegener's granulomatosis and limited from of Wegener's granulomatosis which is absent of renal invovement. The treatment of choice is cyclophosphamide therapy with or without corticosteroid in this disease. The authors, recently, have observed 1 case of classic form and 3 cases of limited form of Wegener's granulomatosis and report these with literature review.
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