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Korean Journal of Otorhinolaryngology-Head and Neck Surgery > Volume 32(2); 1989 > Article
Korean Journal of Otorhinolaryngology-Head and Neck Surgery 1989;32(2): 252-7.
A Clinical Observations of Epithelial Migration on the Human Tympanic Membrane
Hae Song Kim, MD, Yong Bum Cho, MD, and Chong Won Lee, MD
Department of Otolaryngology, College of Medicine, Chonnam National University, Korea
한국 정상 성인에 있어서 고막 상피의 이동현상에 대한 고찰
김해송 · 조용범 · 이종원
전남대학교 의과대학 이비인후과학교실
ABSTRACT

Epithelial migration on the tympanic membrane and external auditory canal is a very important self-cleansing property of the outer ear. In order to evaluate the pattern and rate of epithelial migration, 83 ears of 42 normal persons were examed. India ink(0.5%) was used as a marker. The dye was applied to the umbo, handle of malleus, the lateral process of the malleus and four quadrants with a applicator. Changes in locations of the dye were observed at 1 week interval under an operating microscope. Photograph and linedrawing were taken. The migratory rate on the tympanic membrane was calculated by measuring the distance between the orginal marker and the various migrated point. The obtained results were as follows. 1) Overall patterns in epithelial migration were classified into two types : a curved pattern(type I, 82,8%) and a straight pattern (type II, 17.2%). A curved pattern was classified into two types. The first type was a clockwise rotation pattern in right ears and a counterclockwise rotation pattern in left ears(type Ia, 44.0%). The second type showed a counterclockwise rotation pattern in right ears and a clockwise rotation pattern in left ears(type Ib, 38.8%). 2) The migratory rate was increased on approaching the annulus. It was fastest in the anterior-inferior quadrant(135um/day) and latest in the posterior-superior quadrant (80um/day). 3) The patterns and rates of migration in similar regions of both tympanic membranes of an individual were found to be similar. 4) Some desquamation was found in four ears(4.8%) and total desquamation in two ears(2.4%). 

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