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Korean Journal of Otorhinolaryngology-Head and Neck Surgery 1990;33(1): 111-5. |
| Therapeutic Effect of Loratadine in Allergic Rhinitis |
| Soon Il Park, MD, Joon Kwon, MD, Jeong Pyo Bong, MD, and Yang Sang Lim, MD |
| Department of Otolaryngology, Yonsei University Wonju College of Medicine, Korea |
| 알레르기성 비염에 대한 Loratadine의 치료효과 |
| 박순일 · 권 준 · 봉정표 · 임양상 |
| 연세대학교 원주의과대학 이비인후과학교실 |
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| ABSTRACT |
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Twenty patients with allergic rhinitis had been treated with LORATADINE(CLARITYNE) for 4 weeks. LORATADINE is a competitive antagonist of histamine at H1 receptors. It effectively blocks the action of histamine in tissues that undergo allergic reactions. The clinical efficacy of therapy was excellent in 6 cases(30%) and good in 10 cases(50%). The total symtom scores were reduced significantly. The side effect such as somnolence, dry mouth, and gastrointestinal disturbance was not occurred. It was suggested that LORATADINE is effective and safe drug for management of allergic rhinitis.
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