Effects of Lateral Semicircular Canal Occlusion in Guinea Pigs on Auditory Brainstem Response |
Boo Hyun Nam, MD, Jang Yourl Yoo, MD, and Chan Il Park, MD |
Department of Otolaryngology, College of Medicine, Chungnam National University, Daejeon, Korea |
기니픽에서 외측반규관의 폐쇄가 청성뇌간유발반응에 미치는 영향 |
남부현 · 유장렬 · 박찬일 |
충남대학교 의과대학 이비인후과학교실 |
|
|
|
ABSTRACT |
Serial recordings of ABR in eight guinea pigs were performed after lateral semicircular canal destruction and muscle piece plugging procedure. Spontaneous nystagmus toward the nonoperated side was developed following the procedure, and which was disappeared on the next day in all animals. Seven animals showed a little threshold change in serial recordings of ABR, but one animal developed profound hearing loss on the tenth postoperative day. Preservation of hearing after lateral semicircular canal destruction and canal occlusion procedure in guinea pigs suggests the possibility of its clinical application.
|
Keywords:
ABRㆍLateral semicircular canal destructionㆍPreservation of hearing |
|