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Korean Journal of Otorhinolaryngology-Head and Neck Surgery 1995;38(3): 330-3. |
Experimentally Induced Aural Cholesteatoma in the Gerbil |
Hong-Joon Park, MD, Young-Myoung Chun, MD, and Keehyun Park, MD |
Department of Otolaryngology, Ajou University School of Medicine, Seoul ,Korea |
외이도 진주종의 실험적 유발 |
박홍준 · 전영명 · 박기현 |
아주대학교 의과대학 이비인후과학교실 |
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ABSTRACT |
There have been several studies using experimental animal models to clarify the characteristics of human cholesteatoma. Among the methods, ligation of the external auditory canal in the gerbil was realized to be easy to induce the cholesteatoma and presented many similaritied with human cholesteatoma. In this study, we could induce the aural cholesteatoma by ligation of the external auditory canal in gerbils. The stages of cholesteatoma were closely related to the duration of ligation and significant bony destruction occurred with inflammation.
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Keywords:
CholesteatomaㆍCanal ligationㆍMongolian gerbil. |
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