|
Korean Journal of Otorhinolaryngology-Head and Neck Surgery 1991;34(1): 5-14. |
Electron microscopic study of utricular macula in alloxan diabetic rat. |
In Won Chang, Young Chae Yu, Jeong Seob Choi, Chul Ho Chang, Chang Joong Jeong, Yong Bum Cho |
|
Alloxan 당뇨 흰쥐의 난형낭 평형반에 대한 전자현미경적 연구 |
장인원1 · 유영채1 · 최정섭1 · 장철호2 · 정찬중1 · 조용범1 |
전남대학교 의과대학 이비인후과학교실1;원광대학교 의과대학 이비인후과학교실2; |
|
|
|
ABSTRACT |
Diabetic patients occasionally complains of dizziness and vertigo, which suggests derrangement of vestibular function of inner ear. To examine whether diabetic condition has any relation with the a fine morphology of utricular macula which is the important mechanoreceptor of equilibrium, light and electron microscopic observations were made on neuroepithelium, type I and II hair cells of utricular macula as well as on vestibular nerve in alloxan induced diabetic rats. Abnormal features found were as follows: 1) Myelin lamella of utricular nerve shows frequent interruption, irregular running and ballooning. 2) Otolithic membrane is fractured and fragmented. 3) Chalice of type I hair cell of utricle is swollen. It is suggested that fine morphological changes in the utricular components of alloxan diabetic rat are closely related with the macular function.
|
|
|
|