The clinicopathologic features of seven patients with Kimura's disease and two patients with epithelioid hemangioma were studied and compared. The common features shared by both conditions included predilection for the head and neck region, tendency to recur, and vascular nature of the lesion with lymphoid and eosinophilic infiltrates. However, Kimura's disease was usually seen for a longer duration and occurred as a deeply seated, larger soft tissue mass, with frequent involvement of lymph nodes and major salivary glands. In addition, it was often accompanied by peripheral blood eosinophilia and serum IgE level elevation. In contrast, epithelioid hemangioma lesions were small dermal papular or nodular eruptions present for a shorter duration. They were not accompanied by peripheral blood eosinophilia. The main histopathological difference was the presence of ""vacuolated"" endothelial cells in epithelioid hemangioma but not in Kimura's disease. Kimura's disease was characterized by eosinophillic infiltration, especially the formation of eosinophilic microabscesses and fibrosis.