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Korean Journal of Otorhinolaryngology-Head and Neck Surgery > Epub ahead of print

doi: https://doi.org/10.3342/kjorl-hns.2026.00437    [Epub ahead of print]
Successful Treatment of Postauricular Muscle Myokymia Using Low-Dose Botulinum Toxin Type A
Han-Seul Na1 , Seokhwan Lee1 , Sung-Won Choi1,2 , Se-Joon Oh1,2
1Department of Otorhinolaryngology and Biomedical Research Institute, Pusan National University Hospital, Busan, Korea
2Department of Otorhinolaryngology, Pusan National University School of Medicine, Busan, Korea
저용량 A형 보툴리눔 독소를 이용한 후이개근 근떨림증의 치료 1예
나한슬1 , 이석환1 , 최성원1,2 , 오세준1,2
1부산대학교병원 이비인후과 및 의생명연구원
2부산대학교 의과대학 이비인후과학교실
Correspondence  Se-Joon Oh ,Tel: +82-51-240-7824, Email: o3jdoc@hanmail.net
Received: 27 May 2026; Revised: July 4, 2026   Accepted: 15 July 2026.  Published online: 21 October 2026.
ABSTRACT
Postauricular muscle myokymia is a rare focal movement disorder caused by involuntary activation of the posterior auricular muscle. We report a 44-year-old woman with a 2-year history of intermittent bursts of rapid, irregular twitching localized to the right postauricular region, which aggravated when lying on her right side or turning her head rightward. Oxcarbazepine was ineffective. In a single injection session, botulinum toxin type A (Nabota, 10 U in 0.2 mL; 50 U/mL) was administered into the posterior auricular muscle. Given the small size and superficial location of the muscle, a concentrated, low-volume formulation was chosen to confine the toxin to the target area. Symptoms markedly improved within 3 days and resolved completely by day 5. Visual Analogue Scale decreased from 5 to 0 at 2 weeks, remained 0 at 3 months, and was 1 at 6 months without requiring further treatment. No adverse effects occurred. This case illustrates that the botulinum toxin type A can be a safe and effective option for focal postauricular muscle myokymia when the symptomatic muscle is accurately identified.
Keywords: Botulinum toxin type Aㆍ Botulinum toxin injectionㆍ Movement disorderㆍ Postauricular myokymiaㆍ Posterior auricular muscle
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